6-Aminoquinolyl-N-hydroxysuccinimidyl carbamate (CAS 148757-94-2): The Gold Standard for Amino Acid Analysis
Finetech Industry Limited is proud to offer high-purity 6-Aminoquinolyl-N-hydroxysuccinimidyl carbamate (AQC), a premier derivatizing reagent widely recognized for its unparalleled sensitivity and stability in amino acid and protein analysis.
Whether you are conducting food safety testing, pharmaceutical research, or clinical diagnostics, our AQC reagent ensures reproducible results and high-resolution chromatographic peaks.
1. Chemical Identity and Specifications
Understanding the technical profile of your reagents is crucial for experimental precision.
Common Name: AQC / 6-Aminoquinolyl-N-hydroxysuccinimidyl carbamate
CAS Number: 148757-94-2
Molecular Formula: C14H11N3O4
Molecular Weight: 285.25 g/mol
Purity: ≥98% (HPLC)
Applications: Pre-column derivatization for HPLC/UPLC and Mass Spectrometry (MS).
2. Key Applications in Analytical Chemistry
High-Sensitivity Amino Acid Analysis (AAA)
AQC is the industry-standard reagent for pre-column derivatization. It reacts rapidly with primary and secondary amines, forming highly stable, fluorescent derivatives. This allows for:
Enhanced Detection Limits: Detect trace levels of amino acids in complex matrices.
Rapid Reaction: Complete derivatization occurs in minutes at moderate temperatures.
Sample Stability: Derivatized samples remain stable for days, facilitating high-throughput automated analysis.
Protein and Peptide Sequencing
Researchers utilize CAS 148757-94-2 for the N-terminal analysis of proteins. Its ability to provide clear, distinct signals makes it a favorite for biochemical laboratories focusing on proteomics.
Food and Beverage Testing
AQC is vital for quantifying nutritional content and monitoring fermentation processes by measuring free amino acid profiles in food products.
3. Why Source from Finetech Industry Limited?
At Finetech Industry Limited, we bridge the gap between high-end chemical synthesis and practical laboratory needs.
Superior Stability: Our AQC is synthesized and stored to prevent moisture-induced degradation, ensuring a long shelf life.
Zero Interference: Optimized purification processes ensure no residual "ghost peaks" during your HPLC runs.
Bulk & Custom Packaging: From milligram-scale research to kilogram-scale industrial production, we accommodate your specific requirements.
Global Logistics: Fast, compliant shipping with full documentation (COA, MSDS, and HPLC reports).
4. Frequently Asked Questions (FAQ)
Q: Why choose AQC over OPA or FMOC derivatization?
A: Unlike OPA (which doesn't detect secondary amines) or FMOC (which requires tedious extraction of excess reagent), AQC reacts with both primary and secondary amines and produces stable by-products that do not interfere with chromatography.
Q: What are the optimal storage conditions for CAS 148757-94-2?
A: To maintain maximum activity, it should be stored in a dry, dark place at -20°C.
Q: Can AQC be used with Mass Spectrometry (LC-MS)?
A: Yes, AQC derivatives are highly compatible with ESI-MS, providing excellent ionization efficiency.
5. Summary
For laboratories demanding the highest accuracy in amino acid profiling, 6-Aminoquinolyl-N-hydroxysuccinimidyl carbamate (CAS 148757-94-2) from Finetech Industry Limited is the ultimate choice.
Optimize your analytical workflow today.
Keywords: Amino Acid Derivatization, AQC Reagent, CAS 148757-94-2, HPLC Analysis, Protein Sequencing.