Finetech Industry Limited: Islatravir (CAS 865363-93-5) Supplier
Finetech Industry Limited: Islatravir (CAS 865363-93-5) Supplier
Explore high-quality Islatravir from Finetech Industry Limited. This potent synthetic nucleoside analogue is a valuable tool for cutting-edge antiviral therapy research, cancer studies, and chemical biology applications.
Product Overview: Islatravir
Islatravir is a synthetic compound belonging to the class of nucleoside analogues. It is a modified form of the natural nucleoside adenosine, engineered with specific chemical modifications to enhance its stability, bioavailability, and therapeutic potential.
Key Specifications
| Property | Detail |
|---|---|
| Product Name | Islatravir 4'-ethynyl-2-fluoro-2'-deoxyadenosine |
| CAS Number | 865363-93-5 |
| Formula | C₁₂H₁₂FN₅O₃ |
| Molecular Weight | 293.25 g/mol |
| Chemical Class | Synthetic Nucleoside Analogue |
| Structure Modifications | Ethynyl group at the 4' carbon position; Fluorine atom at the 2' carbon position. |
| Properties | Enhanced stability, increased resistance to enzymatic degradation, enhanced lipophilicity. |
Structure and Properties
Islatravir is derived from the nucleoside adenosine through the introduction of an ethynyl group (-C≡CH) at the 4' carbon position and a fluorine atom (F) at the 2' carbon position. These strategic modifications confer unique physicochemical properties that distinguish it from its natural counterpart.
- Enhanced Stability: The ethynyl group increases stability and resistance to enzymatic degradation.
- Improved Bioavailability: The fluorine atom enhances lipophilicity, potentially improving cellular uptake and bioavailability for therapeutic applications.
Versatile Applications of Islatravir (CAS 865363-93-5)
The unique structure and properties of this compound make it highly valuable across multiple scientific fields, particularly in medicinal chemistry and biotechnology.
1. Antiviral Activity Research (especially HIV)
Islatravir has demonstrated significant broad-spectrum antiviral activity, notably as a potent HIV non-nucleoside reverse transcriptase inhibitor. It functions by interfering with the viral polymerase enzyme, effectively inhibiting viral replication.
- Efficacy: Shown efficacy against both DNA and RNA viruses.
- Target Viruses: Includes research targets such as Hepatitis B virus (HBV) and Human Immunodeficiency Virus (HIV).
2. Cancer Research & Therapeutics
The compound exhibits potent antiproliferative activity against various cancer cell lines. Its ability to inhibit cell growth, induce apoptosis (programmed cell death), and selectively target cancer cells while sparing normal cells positions it as a potential candidate for novel cancer therapies.
3. Nucleoside Analogue Probes & Diagnostics
The terminal ethynyl group is a functional handle ideal for click chemistry applications. This enables easy attachment of various probes, fluorescent markers, or functional groups for:
- Molecular imaging
- Diagnostics development
- Targeted therapy research
4. Nucleic Acid Modification & Chemical Biology
The modified structure allows for direct incorporation into nucleic acids during DNA or RNA synthesis. Researchers utilize this property in chemical biology to study fundamental aspects of nucleic acid structure, function, and interactions.
Conclusion
Islatravir is a robust synthetic nucleoside analogue with unique properties and promising applications in antiviral therapy, cancer research, nucleic acid modification, and molecular imaging. Its structural modifications enhance stability and efficacy, making it a valuable tool for scientific investigation and future medical advancements.
Ordering & Supply Information
Finetech Industry Limited ensures a consistent supply of high-quality Islatravir (CAS 865363-93-5) for academic and industrial R&D.
Contact us today to receive a quote or discuss your supply needs:
Email: sales@finetechnology-ind.com
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- C₁₂H₁₂FN₅O₃