Ethyl 2-Chloropyrimidine-5-carboxylate Supplier – 98% Purity Chlorinated Pyrimidine Building Block for Pharmaceutical Research | CAS 89793-12-4 | Finetech Industry Limited

1. Product Overview

Ethyl 2-chloropyrimidine-5-carboxylate (CAS No. 89793-12-4) is a chlorinated pyrimidine derivative used as a versatile heterocyclic building block in organic synthesis and pharmaceutical intermediate development. Its molecular structure contains a pyrimidine ring substituted with a chlorine atom at the 2-position and an ethyl carboxylate group at the 5-position.

The combination of these functional groups provides opportunities for further molecular modification. The chlorine substituent on the electron-deficient pyrimidine ring can serve as a reactive site for nucleophilic aromatic substitution, while the ester functionality can undergo transformations such as hydrolysis and conversion into other carboxylic acid derivatives.

These complementary reaction sites make Ethyl 2-chloropyrimidine-5-carboxylate a useful starting material for preparing substituted pyrimidine compounds, nitrogen-containing heterocycles, and more complex molecular structures.

Finetech Industry Limited supplies Ethyl 2-chloropyrimidine-5-carboxylate with a specified purity of 98%, suitable for pharmaceutical research, medicinal chemistry, heterocyclic synthesis, and specialty chemical development.

2. Product Specifications

3. Chemical Characteristics and Structural Features

Ethyl 2-chloropyrimidine-5-carboxylate belongs to the family of substituted pyrimidine compounds. Its synthetic versatility is mainly associated with the reactivity of the chlorinated pyrimidine ring and the presence of an ester functional group.

2-Chloropyrimidine Structure

The pyrimidine ring contains two nitrogen atoms, which contribute to its electron-deficient heteroaromatic character. The chlorine atom at the 2-position provides a potential reaction site for nucleophilic aromatic substitution, allowing researchers to introduce different nucleophilic groups under suitable reaction conditions.

This feature supports the preparation of diverse 2-substituted pyrimidine derivatives.

Ethyl Carboxylate Functionality

The ethyl ester group at the 5-position provides an additional functional handle for chemical modification. It can be converted into the corresponding carboxylic acid through hydrolysis or used in other ester-related transformations.

These reactions provide opportunities to prepare pyrimidine-5-carboxylic acid derivatives, amides, and other functionalized compounds.

Two Complementary Reaction Sites

The combination of the 2-chloro substituent and 5-ethyl carboxylate group allows researchers to explore different reaction sequences and substitution patterns. This makes the compound a practical intermediate for the synthesis of structurally diverse pyrimidine derivatives.

4. Research Applications of Ethyl 2-Chloropyrimidine-5-carboxylate

4.1 Pharmaceutical Intermediate Development

Pyrimidine rings are common structural components in pharmaceutical research and medicinal chemistry. Substituted pyrimidines are frequently investigated in the development of biologically active molecular structures.

Ethyl 2-chloropyrimidine-5-carboxylate can serve as a starting intermediate for preparing functionalized pyrimidine derivatives. Its two reactive structural features provide opportunities for introducing different substituents and modifying the molecular framework during pharmaceutical intermediate development.

4.2 Heterocyclic Chemistry and Nucleophilic Substitution

The chlorine atom at the 2-position of the pyrimidine ring provides a useful reaction site for nucleophilic aromatic substitution under appropriate conditions.

Researchers can investigate the introduction of nitrogen-, oxygen-, or sulfur-containing substituents to generate different 2-substituted pyrimidine derivatives.

Such transformations are useful in heterocyclic chemistry, synthetic route development, and the preparation of compound libraries.

4.3 Medicinal Chemistry and Molecular Diversification

The pyrimidine scaffold is widely used in medicinal chemistry because it provides a nitrogen-containing aromatic framework that can be modified at different positions.

Ethyl 2-chloropyrimidine-5-carboxylate supports molecular diversification through modification of both the 2-position and the 5-position functional groups. Researchers can use these transformations to prepare structural analogues and investigate how different substituents influence molecular properties and biological activity.

4.4 Pyrimidine Carboxylic Acid and Amide Derivative Synthesis

The ethyl ester group at the 5-position can be hydrolyzed to produce the corresponding pyrimidine carboxylic acid. The resulting acid functionality can then be used in further transformations, including amide formation and other coupling reactions.

This provides a useful synthetic pathway toward pyrimidine-containing amides and related derivatives for pharmaceutical and specialty chemical research.

4.5 Agrochemical and Specialty Chemical Research

Substituted nitrogen-containing heterocycles are also explored in agrochemical discovery and specialty chemical development.

Ethyl 2-chloropyrimidine-5-carboxylate can serve as a synthetic building block in research programs involving functionalized pyrimidine structures and the development of new heterocyclic compounds. Its suitability for a particular application depends on the target structure and the selected synthetic route.

5. Ethyl 2-Chloropyrimidine-5-carboxylate Supply from Finetech Industry Limited

Finetech Industry Limited supplies Ethyl 2-chloropyrimidine-5-carboxylate (CAS 89793-12-4), with a specified purity of 98%, for customers involved in pharmaceutical research, organic synthesis, and specialty chemical development.

Product information includes:

1. Specified purity: 98%.
2. Appearance: Pale yellow solid.
3. Quality control: ¹H-NMR and HPLC.
4. Product identification: CAS 89793-12-4 and product code FT-0650141.
5. Application areas: Pharmaceutical intermediate development, pyrimidine chemistry, heterocyclic synthesis, and medicinal chemistry research.

Finetech Industry Limited supports customers seeking specialty heterocyclic compounds and chemical building blocks for laboratory research, synthetic development, and commercial sourcing requirements.

For packaging options, current availability, and larger quantity inquiries, please contact our sales team.

6. Why Choose Finetech Industry Limited?

Finetech Industry Limited supplies specialty chemicals, heterocyclic building blocks, pharmaceutical intermediates, and research reagents to customers worldwide.

Our services focus on:

1. A broad selection of heterocyclic compounds and pharmaceutical research intermediates.
2. Product quality control supported by appropriate analytical methods.
3. Flexible sourcing and chemical supply solutions.
4. Professional communication and technical product support.
5. International shipping coordination for global customers.

We aim to provide reliable chemical supply, responsive service, and long-term cooperation for pharmaceutical companies, research organizations, and chemical manufacturers.

7. Contact Finetech Industry Limited

For quotations, product availability, technical information, or sourcing inquiries regarding Ethyl 2-chloropyrimidine-5-carboxylate (CAS 89793-12-4), please contact Finetech Industry Limited.

Product Number: FT-0650141

Product Name: Ethyl 2-chloropyrimidine-5-carboxylate

CAS Number: 89793-12-4

Purity: 98%

Appearance: Pale yellow solid

Quality Control: ¹H-NMR and HPLC

Website: https://www.finetechnology-ind.com/

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