Elevate Formulation Stability with Cas:51166-71-3 DMCD from Finetech Industry Limited
In
the evolving landscape of pharmaceutical and supramolecular research, the
demand for high-efficiency solubilizers is paramount. Finetech Industry
Limited is proud to supply 2,6-Di-O-Methyl-Beta-Cyclodextrin (DMCD)—a
chemically modified, hydrophilic cyclic oligosaccharide engineered for superior
inclusion complexation.
With
selective methylation at the C-2 and C-6 positions, DMCD overcomes the
limitations of native beta-cyclodextrin, offering unmatched solubility and
molecular stabilization for lipophilic compounds.
Technical Specifications
CAS
Number:
51166-71-3
Molecular
Formula:
C56H98O35
Molecular
Weight:
1331.36 g/mol
Product
Quality:
High-purity research and industrial grade
Why Choose DMCD? Key Advantages for Researchers
Traditional
beta-cyclodextrins often face limitations regarding solubility and cavity
flexibility. DMCD addresses these challenges through:
Enhanced
Aqueous Solubility:
Dramatically increases the dissolution rate of hydrophobic Active
Pharmaceutical Ingredients (APIs).
Superior
Inclusion Performance:
The hydrophobic inner cavity (7-8) provides a more favorable environment for
guest molecules compared to non-methylated counterparts.
Advanced
Chiral Recognition:
Exceptional performance in analytical chemistry for the separation of
enantiomers.
Thermal
& Chemical Stability:
Protects volatile or sensitive compounds from oxidation and degradation.
Multi-Industry Applications
1. Pharmaceutical Formulation & Bioavailability
DMCD
is a cornerstone in drug delivery systems. By forming stable inclusion
complexes, it improves the pharmacokinetics of poorly soluble drugs.
Research indicates that methylated cyclodextrins can significantly enhance the
permeability of drugs across biological membranes.
Literature
Support:
Uekama et al. (1998) demonstrated that methylated beta-cyclodextrins
effectively improve the bioavailability of fat-soluble vitamins and steroid
hormones by modulating their release profiles.
2. Analytical & Separation Sciences
In
chromatography (HPLC/GC), DMCD acts as a powerful chiral selector. Its ability
to distinguish between optical isomers makes it indispensable for
pharmaceutical quality control and metabolic studies.
3. Food & Cosmetic Technology
Flavor
Retention:
Encapsulates essential oils to prevent volatilization.
Active
Delivery:
Stabilizes antioxidants (like Vitamin C and Retinol) in cosmetic serums,
ensuring long-term efficacy and controlled skin absorption.
Scientific Background & References
The
efficacy of 2,6-Di-O-Methyl-Beta-Cyclodextrin is well-documented in
supramolecular chemistry. Its unique structure allows for a
"distorted" cone shape that often provides better fitting for guest
molecules than hydroxypropyl derivatives.
J.
Szejtli, "Introduction and General Overview of Cyclodextrin Chemistry,"
Chemical Reviews, 1998.
T.
Loftsson and M.E. Brewster, "Pharmaceutical Applications of
Cyclodextrins," Journal of Pharmaceutical Sciences, 1996.
Why Partner with Finetech Industry Limited?
As
a leading supplier of specialty chemicals, Finetech Industry Limited
ensures that every batch of DMCD meets rigorous quality standards. We provide:
Global
Shipping:
Reliable logistics for international research labs and manufacturers.
Technical
Support:
Expert guidance on molar ratios and complexation methods.
Competitive
Pricing:
Scalable solutions from MG-scale research to bulk industrial supply.