Ammonium Salicylate (CAS 528-94-9), also known as Ammonium 2-hydroxybenzoate or Salicylic Acid Ammonium Salt, is an important aromatic organic salt formed by neutralizing salicylic acid with ammonia. Owing to its excellent water solubility, chemical stability, and reactive ortho-hydroxyl functional group, it is widely employed in organic synthesis, analytical chemistry, pharmaceutical research, and fine chemical manufacturing.

Finetech Industry Limited supplies high-purity Ammonium Salicylate (≥98%) for laboratory research, pilot-scale development, and industrial production.

Chemical Information

Applications of Ammonium Salicylate

1. Pharmaceutical Intermediate

Ammonium Salicylate is widely used as an intermediate in pharmaceutical research because the salicylate structure provides excellent synthetic flexibility.

Researchers employ this compound in the preparation of various aromatic intermediates that are subsequently converted into pharmaceutical ingredients, agrochemical intermediates, and specialty fine chemicals.

Its high purity and excellent batch consistency make it suitable for both laboratory synthesis and process optimization studies.

2. Organic Synthesis

One of the most important applications of Ammonium Salicylate (CAS 528-94-9) is its use as a starting material for preparing substituted salicylic acid derivatives.

Typical downstream products include:

1. Salicylamide derivatives
2. Hydroxybenzene intermediates
3. Aromatic amides
4. Specialty organic intermediates
5. Fine chemical building blocks

Because the molecule contains both hydroxyl and carboxyl functional groups, it provides numerous opportunities for esterification, amidation, and substitution reactions in medicinal chemistry.

3. Analytical Chemistry

Ammonium Salicylate is also associated with the well-established salicylate colorimetric method for ammonia determination.

In analytical laboratories, salicylate-based reagents are commonly used for measuring ammonia nitrogen in:

1. Wastewater
2. Environmental water samples
3. Soil extracts
4. Biological samples
5. Agricultural testing

The analytical method is valued for its high sensitivity, low detection limits, and reproducibility.

High-purity raw materials help minimize analytical interference and improve the stability of prepared reagents.

4. Research Applications

In academic laboratories, Ammonium Salicylate is frequently used for:

1. Organic reaction development
2. Pharmaceutical intermediate synthesis
3. Method development
4. Analytical reagent preparation
5. Chemical education and laboratory research

Its relatively simple molecular structure also makes it useful in studies involving aromatic substitution reactions and salicylic acid chemistry.

Advantages of High-Purity Ammonium Salicylate

For research and industrial production, raw material quality directly influences reaction efficiency and product consistency.

High-purity Ammonium Salicylate offers several advantages:

1. ≥98% assay
2. Excellent batch-to-batch consistency
3. Low impurity profile
4. Good water solubility
5. Stable storage characteristics
6. Suitable for laboratory and industrial applications

These characteristics help reduce unwanted side reactions and improve reproducibility during synthesis and analytical procedures.

Quality Supply from Finetech Industry Limited

Finetech Industry Limited manufactures and supplies Ammonium Salicylate (CAS 528-94-9) with strict quality control procedures.

Our products are available in research quantities as well as bulk commercial volumes and are accompanied by complete documentation, including:

1. Certificate of Analysis (COA)
2. Safety Data Sheet (SDS)
3. Technical Data Sheet (TDS)
4. Batch traceability documentation

We support customers in pharmaceutical research, analytical laboratories, universities, chemical distributors, and industrial manufacturers worldwide.

Frequently Asked Questions

What is Ammonium Salicylate?

Ammonium Salicylate is the ammonium salt of salicylic acid with CAS number 528-94-9. It is commonly used in organic synthesis, analytical chemistry, and pharmaceutical research.

What is Ammonium Salicylate used for?

Its primary applications include:

1. Pharmaceutical intermediates
2. Organic synthesis
3. Analytical reagents
4. Chemical research
5. Fine chemical manufacturing

Is Ammonium Salicylate water soluble?

Yes. Compared with salicylic acid, Ammonium Salicylate exhibits significantly higher water solubility, making it suitable for aqueous laboratory applications.

What purity is available?

Finetech Industry Limited supplies Ammonium Salicylate with a purity of ≥98%, suitable for research and industrial applications.

References

1. The Merck Index, 15th Edition. Royal Society of Chemistry.
2. PubChem Compound Summary: Ammonium Salicylate.
3. Journal of Chemical & Engineering Data. Studies on the Solubility and Thermodynamic Properties of Organic Acid Salts.
4. CRC Handbook of Chemistry and Physics.