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2,5-Dichloropyrazine,CAS No :19745-07-4: Synthesis and Diverse Applications

2,5-Dichloropyrazine, CAS:19745-07-4 also known as 2,5-Dichloro-1,4-diazine, is a pharmaceutical intermediate with a molecular formula of C4H2Cl2N2 and a molecular weight of 148.98. This compound holds significant importance in various applications, and its synthesis process involves the chlorination of pyrazine-2-amine to obtain 5-chloropyrazine-2-amine, followed by diazotization to yield 2,5-Dichloropyrazine.Synthesis Process: The synthesis of 5-chloropyrazine-2-amine involves the addition of N-chlorosuccinimide (NCS) to a stirred solution of pyrazine-2-amine in anhydrous dichloromethane un [...]

Jan 21, 2026 Product News 1544 Views Read More

Versatile Applications of 1-Amino-3,3-Diethoxypropane,Cas:41365-75-7 in Organic Synthesis and Biomedical Research

1-Amino-3,3-diethoxypropane,Cas:41365-75-7 also known as ADEP, is an organic compound with the chemical formula C7H17NO2. It is a colorless liquid commonly used as a reagent in organic synthesis. Additionally, it is an effective modulator of alginate and chitosan-based hydrogels and is utilized for the delivery of bone marrow stromal cells (BMSCs) for cartilage regeneration[1]. This compound possesses many important chemical properties and applications, which will be detailed below.Firstly, 1-Amino-3,3-diethoxypropane is an important reagent in organic synthesis. It can be [...]

Jan 21, 2026 ---- News 951 Views Read More

Exploring the Diverse Uses of Aminopterin: From Leukemia Treatment to Cell Culture

Aminopterin,cas: 54-62-6 also known as 4-aminopteroic acid, is a synthetic derivative of pterin and a 4-amino derivative of folic acid. It is an antineoplastic drug with immunosuppressive properties, often used in chemotherapy. Aminopterin functions as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase, effectively blocking tetrahydrofolate synthesis. This leads to the depletion of nucleotide precursors and the inhibition of DNA, RNA, and protein synthesis.Discovered by Yellapragada Subbarow, Aminopterin was first used by Sidney Farber in [...]

Jan 21, 2026 Product News 1352 Views Read More