5-Fluoro-2-Picolinic Acid Supplier – 99% High-Purity Fluorinated Pyridine Building Block for Pharmaceutical Research and Organic Synthesis | Finetech Industry Limited
1. Product Overview
5-Fluoro-2-picolinic acid (CAS No. 107504-08-5) is a fluorinated pyridine carboxylic acid widely used as a heterocyclic building block in organic synthesis and pharmaceutical research. Also known as 5-fluoropyridine-2-carboxylic acid, this compound combines a pyridine ring, a fluorine substituent at the 5-position, and a carboxylic acid functional group at the 2-position.
The combination of these structural features makes 5-Fluoro-2-picolinic acid a useful intermediate for preparing substituted pyridine derivatives and more complex molecular structures. Its carboxylic acid group provides a site for further chemical transformations, while the fluorine substituent offers an additional structural modification point for molecular design.
Finetech Industry Limited supplies 5-Fluoro-2-picolinic acid with an assay of 99.0%, suitable for pharmaceutical intermediate development, medicinal chemistry, heterocyclic synthesis, and other research applications. Kilogram-scale packaging and larger-scale production are available.
2. Product Specifications
| ParameterSpecification | |
| Product Name | 5-Fluoro-2-picolinic acid |
| Product Number | FT-0649116 |
| CAS Number | 107504-08-5 |
| Synonym | 5-Fluoropyridine-2-carboxylic acid |
| Molecular Formula | C₆H₄FNO₂ |
| Molecular Weight | 141.10 g/mol |
| Appearance | White solid |
| Assay | 99.0% |
| Identification / Quality Control | ¹H-NMR, HPLC |
| Storage Conditions | 2–8°C, protect from light, keep tightly sealed |
| Available Packaging | 1 kg, 5 kg, 25 kg |
| Supply Capability | Kilogram-scale supply and larger-scale production |
3. Chemical Characteristics and Structural Features
5-Fluoro-2-picolinic acid belongs to the family of fluorinated pyridine carboxylic acids. Its molecular structure contains three important elements that contribute to its synthetic utility.
Fluorinated Pyridine Ring
The pyridine ring is a common heterocyclic framework in pharmaceutical and agrochemical research. Introducing fluorine at the 5-position provides a way to modify the electronic characteristics and molecular properties of the heterocyclic scaffold. Fluorinated pyridine derivatives are frequently explored in medicinal chemistry and the development of functional organic molecules.
Carboxylic Acid Functional Group
The carboxylic acid group at the 2-position can participate in a range of established organic transformations. These include esterification, amide formation, and other carboxylic acid-based coupling reactions. Such transformations allow researchers to introduce different substituents and construct more complex pyridine-containing compounds.
Versatile Intermediate for Molecular Design
The combination of a fluorinated heterocyclic ring and a reactive carboxylic acid group makes this compound a practical starting material for preparing structurally diverse pyridine derivatives. It can support the development of compound libraries and the exploration of structure–activity relationships in research programs.
4. Research Applications of 5-Fluoro-2-Picolinic Acid
4.1 Pharmaceutical Intermediate Development
Fluorinated pyridine derivatives are important structural motifs in pharmaceutical research. 5-Fluoro-2-picolinic acid can serve as a starting intermediate for synthesizing substituted pyridine compounds, including derivatives designed for further biological evaluation.
Its carboxylic acid functionality enables researchers to introduce amide, ester, and other related groups, supporting the preparation of diverse molecular structures for early-stage pharmaceutical research.
4.2 Medicinal Chemistry and Structure–Activity Relationship Studies
Fluorine substitution is a widely used strategy in medicinal chemistry. Replacing hydrogen with fluorine can influence molecular electronic properties, lipophilicity, metabolic stability, and intermolecular interactions, although the actual effect depends on the complete molecular structure.
As a fluorinated heterocyclic building block, 5-Fluoro-2-picolinic acid can be incorporated into compound design and analogue synthesis. It is therefore relevant to research programs investigating how changes in pyridine substitution patterns influence the properties of candidate molecules.
4.3 Heterocyclic Chemistry and Organic Synthesis
The pyridine framework is widely used in the preparation of functional heterocyclic compounds. Through carboxylic acid transformations and subsequent synthetic steps, 5-Fluoro-2-picolinic acid can contribute to the synthesis of substituted pyridines and more elaborate nitrogen-containing molecules.
It is suitable for research involving heterocyclic functionalization, intermediate preparation, and the development of new synthetic routes.
4.4 Amide and Ester Derivative Synthesis
The carboxylic acid group provides a convenient functional handle for preparing amide and ester derivatives. These transformations are commonly used in pharmaceutical intermediate synthesis, molecular diversification, and the preparation of functional organic compounds.
Researchers can use this building block to explore different substituents while retaining the 5-fluoropyridine structural framework.
4.5 Agrochemical and Specialty Chemical Research
Fluorinated heterocyclic compounds are also investigated in agrochemical discovery and specialty chemical development. 5-Fluoro-2-picolinic acid may serve as a synthetic intermediate in research exploring new pyridine-based structures and functional molecules.
Its suitability for a particular synthesis depends on the target structure, reaction conditions, and downstream process requirements.
5. 5-Fluoro-2-Picolinic Acid Supply from Finetech Industry Limited
Finetech Industry Limited provides 5-Fluoro-2-picolinic acid (CAS 107504-08-5), with an assay of 99.0%, for research, development, and industrial chemical synthesis requirements.
Our product supply specifications include:
- High assay: 99.0%, with ¹H-NMR and HPLC quality control.
- Multiple packaging options: 1 kg, 5 kg, and 25 kg.
- Production scalability: Kilogram-scale supply with larger-scale production available.
- Storage guidance: Store at 2–8°C, protected from light, in a tightly sealed container.
- International delivery: Global shipping options for qualified business and research customers.
Whether required for laboratory development, pharmaceutical intermediate synthesis, or larger production programs, Finetech Industry Limited can support different purchasing quantities and project requirements.
6. Why Choose Finetech Industry Limited?
Finetech Industry Limited supplies specialty chemicals, pharmaceutical research intermediates, and heterocyclic building blocks for customers involved in chemical synthesis and product development.
Our supply services focus on:
- A broad selection of research chemicals and specialty intermediates.
- Quality control supported by appropriate analytical documentation.
- Flexible packaging from kilogram quantities to larger production requirements.
- Support for custom sourcing and chemical supply projects.
- International shipping coordination for global customers.
We aim to provide reliable product supply, responsive communication, and professional support for long-term business cooperation.
7. Contact Finetech Industry Limited
For pricing, availability, technical specifications, or bulk supply inquiries regarding 5-Fluoro-2-picolinic acid (CAS 107504-08-5), please contact Finetech Industry Limited.
Product Number: FT-0649116
Product: 5-Fluoro-2-picolinic acid
Assay: 99.0%
Packaging: 1 kg / 5 kg / 25 kg
Supply: Larger-scale production available
Website: https://www.finetechnology-ind.com/
Contact our team for quotations, product documentation, and global shipping arrangements.